If you have SELinux installed, typically as part of Fedora Core 3 or 4, then you may experinece difficulties getting GBrowse to work. The default security parameters for SELinux prevent GBrowse from performing some fundamental tasks, including reading its configuration file in /etc/httpd/conf/gbrowse.conf (where /etc/httpd/conf is typically /etc/httpd/conf or /usr/local/apache/conf). While we are working the developers of SELinux to fix this, here are the directions for the current work around: 1. Make sure your security policy is up to date: % yum update selinux-policy-targeted 2. Open System Settings->Security Level and click on the SELinux tab. Click on the HTTPD Service triangle to get the httpd settings, and select "Disable SELinux protection for httpd daemon". 2a. Alternatively, uncheck "Enforcing" to set the enforcement level to permissive. 2b. If you don't have X11, you can do the same as step 2 via the command line: % setsebool -P httpd_disable_trans 1 % system httpd restart After you do this, add the --SELINUX=1 tag when exectuting perl Makefile.PL: % perl Makefile.PL --SELINUX=1 Please let me know if you have any difficulties with this procedure. Scott Cain cain@cshl.org 2/16/05